PIEZO2 Antibody

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ProSci
Product Code: PSI-8613
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-8613-0.02mg0.02mg£150.00
Quantity:
PSI-8613-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
PIEZO2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of PIEZO2 in SK-N-SH cell lysate with PIEZO2 antibody at (A) 1 and (B) 2 μg/mL.
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<strong>WB Validation in Mouse Skeletal Muscle</strong><br> Loading: 15 ug of mouse skeletal muscle lysate Antibodies: PIEZO2 8613-1701, 2 ug/mL , 1 h incubation at RT in 5% NFDM/TBST. Secondary: Goat Anti-Rabbit IgG HRP conjugate at 1:10000 dilution. Exposure: 30 min
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Western blot analysis of PIEZO2 in SK-N-SH cell lysate with PIEZO2 antibody at (A) 1 and (B) 2 μg/mL.
<strong>WB Validation in Mouse Skeletal Muscle</strong><br> Loading: 15 ug of mouse skeletal muscle lysate Antibodies: PIEZO2 8613-1701, 2 ug/mL , 1 h incubation at RT in 5% NFDM/TBST. Secondary: Goat Anti-Rabbit IgG HRP conjugate at 1:10000 dilution. Exposure: 30 min

Documents

Further Information

Additional Names:
PIEZO2 Antibody: C18orf30, C18orf58, DA3, DA5, DAIPT, FAM38B, FAM38B2, HsT748, HsT771, MWKS
Application Note:
PIEZO2 antibody can be used for Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested.
Background:
PIEZO2 is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis.
Buffer:
PIEZO2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PIEZO2 antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human PIEZO2.
NCBI Gene ID #:
63895
NCBI Official Name:
piezo type mechanosensitive ion channel component 2
NCBI Official Symbol:
PIEZO2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 233, 305 kDa

Observed: 235 kDa
Protein Accession #:
NP_071351
Purification:
PIEZO2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cell Cycle,Cancer
SPECIFICITY:
PIEZO2 Antibody is predicted to not cross-react with PIEZO1.
Swissprot #:
Q92508
User NOte:
Optimal dilutions for each application to be determined by the researcher.