MARCH11 Antibody
| Code | Size | Price |
|---|
| PSI-57-285-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
E3 ubiquitin-protein ligase MARCH11, 632-, Membrane-associated RING finger protein 11, Membrane-associated RING-CH protein XI, MARCH-XI, MARCH11
Application Note:
For WB starting dilution is: 1:1000
Background:
MARCH11 is a member of the MARCH family of membrane-bound
E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin
(see MIM 191339) to target lysines in substrate proteins, thereby
signaling their intracellular transport. March11 appears to have a
role in ubiquitin-mediated protein sorting in the trans-Golgi
network (TGN)-multivesicular body (MVB) transport pathway (Morokuma
et al., 2007 [PubMed 17604280]).
Background References:
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Morokuma, Y., et al. J. Biol. Chem. 282(34):24806-24815(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This MARCH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human MARCH11.
NCBI Gene ID #:
441061
NCBI Official Name:
E3 ubiquitin-protein ligase MARCH11
NCBI Official Symbol:
Mar-11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
A6NNE9
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Cell Cycle
Swissprot #:
A6NNE9
User NOte:
Optimal dilutions for each application to be determined by the researcher.