PDCD10 Antibody
| Code | Size | Price |
|---|
| PSI-59-576-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15, PDCD10, CCM3, TFAR15
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes an evolutionarily conserved protein
associated with cell apoptosis. The protein interacts with the
serine/threonine protein kinase MST4 to modulate the extracellular
signal-regulated kinase (ERK) pathway. It also interacts with and
is phosphoryated by serine/threonine kinase 25, and is thought to
function in a signaling pathway essential for vascular developent.
Mutations in this gene are one cause of cerebral cavernous
malformations, which are vascular malformations that cause seizures
and cerebral hemorrhages. Multiple alternatively spliced variants,
encoding the same protein, have been identified. [provided by
RefSeq].
Background References:
- Lauenborg, B., et al. APMIS 118(10):719-728(2010)
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Ding, J., et al. Biochem. Biophys. Res. Commun. 399(4):587-592(2010)
- Zheng, X., et al. J. Clin. Invest. 120(8):2795-2804(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Chicken, Mouse, Rat, Xenopus
Immunogen:
This PDCD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of human PDCD10.
NCBI Gene ID #:
11235
NCBI Official Name:
Programmed cell death protein 10
NCBI Official Symbol:
PDCD10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
Q9BUL8
Protein GI Number:
74733232
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
Q9BUL8
User NOte:
Optimal dilutions for each application to be determined by the researcher.