MGST1 Antibody

ProSci
Product Code: PSI-61-481
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-481-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:4000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:4000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Microsomal glutathione S-transferase 1, Microsomal GST-1, Microsomal GST-I, MGST1, GST12, MGST
Application Note:
For WB starting dilution is: 1:4000
Background:
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds.This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress.
Background References:
  • Zhang,H., IntColorectal Dis 22 (10), 1185-1194 (2007)
  • Prall,W.C., Mech. Ageing Dev. 128 (9), 503-510 (2007)
  • Haines,J.L.,Invest. Ophthalmol. Vis. Sci. 47 (1), 329-335 (2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This MGST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-71 amino acids from the Central region of human MGST1.
NCBI Gene ID #:
4257
NCBI Official Name:
Microsomal glutathione S-transferase 1
NCBI Official Symbol:
MGST1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
18 kDa
Protein Accession #:
P10620
Protein GI Number:
121740
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Cell Cycle,Obesity
Swissprot #:
P10620
User NOte:
Optimal dilutions for each application to be determined by the researcher.