ZMPSTE24 Antibody
| Code | Size | Price |
|---|
| PSI-60-794-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the peptidase M48A family.
The encoded protein is a zinc metalloproteinase involved in the two
step post-translational proteolytic cleavage of carboxy terminal
residues of farnesylated prelamin A to form mature lamin A.
Mutations in this gene have been associated with mandibuloacral
dysplasia and restrictive dermopathy.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Miner, J.H. Am. J. Med. Genet.152A (8), 2140-2141 (2010) :
- Smigiel, R., et al. Am. J. Med. Genet.152A (2), 447-452 (2010) :
- Fontaine-Bisson, B., et al. J. Mol. Med. 88(2):193-201(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-433 amino acids from the C-terminal region of human ZMPSTE24.
NCBI Gene ID #:
10269
NCBI Official Name:
CAAX prenyl protease 1 homolog
NCBI Official Symbol:
ZMPSTE24
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
O75844
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Cell Cycle,Signal Transduction
Swissprot #:
O75844
User NOte:
Optimal dilutions for each application to be determined by the researcher.