DUSP13 Antibody
Code | Size | Price |
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PSI-60-124-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Dual specificity protein phosphatase 13 isoform A, DUSP13A, Branching-enzyme interacting DSP, Muscle-restricted DSP, MDSP, DUSP13, BEDP, DUSP13A, MDSP
Application Note:
For WB starting dilution is: 1:1000
Background:
Members of the protein-tyrosine phosphatase superfamily
cooperate with protein kinases to regulate cell proliferation and
differentiation. This superfamily is separated into two families
based on the substrate that is dephosphorylated. One family, the
dual specificity phosphatases (DSPs) acts on both phosphotyrosine
and phosphoserine/threonine residues. This gene encodes different
but related DSP proteins through the use of non-overlapping open
reading frames, alternate splicing, and presumed different
transcription promoters. Expression of the distinct proteins from
this gene has been found to be tissue specific and the proteins may
be involved in postnatal development of specific tissues. A protein
encoded by the upstream ORF was found in skeletal muscle, whereas
the encoded protein from the downstream ORF was found only in
testis. In mouse, a similar pattern of expression was found.
Multiple alternatively spliced transcript variants were described,
but the full-length sequence of only some were determined.
Background References:
- Kim, S.J., et al. Proteins 66(1):239-245(2007)
- Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
- Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
- Chen, H.H., et al. J. Biol. Chem. 279(40):41404-41413(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DUSP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-173 amino acids from the C-terminal region of human DUSP13.
NCBI Gene ID #:
51207
NCBI Official Name:
Dual specificity protein phosphatase 13 isoform A
NCBI Official Symbol:
DUSP13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
Q6B8I1
Protein GI Number:
74748394
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Cell Cycle,Signal Transduction
Swissprot #:
Q6B8I1
User NOte:
Optimal dilutions for each application to be determined by the researcher.