LALBA Antibody
| Code | Size | Price |
|---|
| PSI-58-026-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Alpha-lactalbumin, Lactose synthase B protein, Lysozyme-like protein 7, LALBA, LYZL7
Application Note:
For IHC-P starting dilution is: 1:25
For WB starting dilution is: 1:1000
For WB starting dilution is: 1:1000
Background:
This gene encodes alpha-lactalbumin, a principal protein
of milk. Alpha-lactalbumin forms the regulatory subunit of the
lactose synthase (LS) heterodimer and beta
1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic
component. Together, these proteins enable LS to produce lactose by
transfering galactose moieties to glucose. As a monomer,
alpha-lactalbumin strongly binds calcium and zinc ions and may
possess bactericidal or antitumor activity. A folding variant of
alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor
and immature cells.
Background References:
- Tolin, S., et al. FEBS J. 277(1):163-173(2010)
- Rosner, H.I., et al. J. Mol. Biol. 394(2):351-362(2009)
- Wang, J., et al. J. Dairy Sci. 91(12):4466-4476(2008)
- Ramboarina, S., et al. J. Am. Chem. Soc. 130(46):15318-15326(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LALBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the Central region of human LALBA.
NCBI Gene ID #:
3906
NCBI Official Name:
Alpha-lactalbumin
NCBI Official Symbol:
LALBA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
16 kDa
Protein Accession #:
P00709
Protein GI Number:
126001
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Immunology
Swissprot #:
P00709
User NOte:
Optimal dilutions for each application to be determined by the researcher.