TYRO3 Antibody

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ProSci
Product Code: PSI-63-138
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-138-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from U-87 MG cell line, using TYRO3 Antibody at 1:1000 at each lane.
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Formalin-fixed and paraffin-embedded human brain tissue reacted with TYRO3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of lysate from U-87 MG cell line, using TYRO3 Antibody at 1:1000 at each lane.
Formalin-fixed and paraffin-embedded human brain tissue reacted with TYRO3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Documents

Further Information

Additional Names:
Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase BYK, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase TIF, TYRO3, BYK, DTK, RSE, SKY, TIF
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Tyrosine kinase 3,mainly expressed in brain,is involved in the protection of neurons from apoptosis. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Background References:
  • Dey, B.R., et al., Gene 209 (1-2), 175-183 (1998).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TYRO3 antibody is generated from rabbits immunized with human recombinant TYRO3 protein.
NCBI Gene ID #:
7301
NCBI Official Name:
Tyrosine-protein kinase receptor TYRO3
NCBI Official Symbol:
TYRO3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
97 kDa
Protein Accession #:
Q06418
Protein GI Number:
1717829
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Immunology,Neuroscience,Signal Transduction
Swissprot #:
Q06418
User NOte:
Optimal dilutions for each application to be determined by the researcher.