ADNP Antibody

ProSci
Product Code: PSI-59-817
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-817-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein, ADNP, ADNP1, KIAA0784
Application Note:
For WB starting dilution is: 1:1000
Background:
Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq].
Background References:
  • Braitch, M., et al. Neuroimmunomodulation 17(2):120-125(2010)
  • Mandel, S., et al. J. Biol. Chem. 282(47):34448-34456(2007)
  • Wu, C., et al. Proteomics 7(11):1775-1785(2007)
  • Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ADNP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 831-860 amino acids from the C-terminal region of human ADNP.
NCBI Gene ID #:
23394
NCBI Official Name:
Activity-dependent neuroprotector homeobox protein
NCBI Official Symbol:
ADNP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
124 kDa
Protein Accession #:
Q9H2P0
Protein GI Number:
24636245
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
Q9H2P0
User NOte:
Optimal dilutions for each application to be determined by the researcher.