COPS3 Antibody

ProSci
Product Code: PSI-63-250
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-63-250-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of COPS3 Antibody in Jurkat, 293 cell line lysates (35ug/lane)
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Western blot analysis of COPS3 using rabbit polyclonal COPS3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the COPS3 gene.

Western blot analysis of COPS3 Antibody in Jurkat, 293 cell line lysates (35ug/lane)
Western blot analysis of COPS3 using rabbit polyclonal COPS3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the COPS3 gene.

Further Information

Additional Names:
COP9 signalosome complex subunit 3, SGN3, Signalosome subunit 3, JAB1-containing signalosome subunit 3, COPS3, CSN3
Application Note:
For WB starting dilution is: 1:1000
Background:
COPS3 possesses kinase activity that phosphorylates regulators involved in signal transduction. This protein phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation.
Background References:
  • Henriksen J., Aagesen T.H., Maelandsmo G.M.,.Oncogene 22:5358-5361(2003)
  • Potocki L., Chen K.-S., Lupski J.R.Genomics 57:180-182(1999)
  • Bech-Otschir D., Kraft R., Huang X.,EMBO J. 20:1630-1639(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat
Immunogen:
This COPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-130 amino acids from the Central region of human COPS3.
NCBI Gene ID #:
8533
NCBI Official Name:
COP9 signalosome complex subunit 3
NCBI Official Symbol:
COPS3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q9UNS2
Protein GI Number:
55976621
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
Q9UNS2
User NOte:
Optimal dilutions for each application to be determined by the researcher.