PAX2 Antibody
| Code | Size | Price |
|---|
| PSI-58-879-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Paired box protein Pax-2, PAX2
Application Note:
For WB starting dilution is: 1:1000
Background:
PAX2 encodes paired box gene 2, one of many human
homologues of the Drosophila melanogaster gene prd. The central
feature of this transcription factor gene family is the conserved
DNA-binding paired box domain. PAX2 is believed to be a target of
transcriptional supression by the tumor supressor gene WT1.
Mutations within PAX2 have been shown to result in optic nerve
colobomas and renal hypoplasia. Alternative splicing of this gene
results in multiple transcript variants.
Background References:
- Monte, N.M., et al. Cancer Res. 70(15):6225-6232(2010)
- Ozcan, A., et al. Arch. Pathol. Lab. Med. 134(8):1121-1129(2010)
- Quick, C.M., et al. Hum. Pathol. 41(8):1145-1149(2010)
- Martinovic-Bouriel, J., et al. Am. J. Med. Genet.152A (4), 830-835 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PAX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human PAX2.
NCBI Gene ID #:
5076
NCBI Official Name:
Paired box protein Pax-2
NCBI Official Symbol:
PAX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q02962
Protein GI Number:
223590261
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
Q02962
User NOte:
Optimal dilutions for each application to be determined by the researcher.