NR0B1 Antibody
| Code | Size | Price |
|---|
| PSI-57-262-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Nuclear receptor subfamily 0 group B member 1, DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1, NR0B1, AHC, DAX1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a protein that contains a DNA-binding
domain. The encoded protein acts as a dominant-negative regulator
of transcription which is mediated by the retinoic acid receptor.
This protein also functions as an anti-testis gene by acting
antagonistically to Sry. Mutations in this gene result in both
X-linked congenital adrenal hypoplasia and hypogonadotropic
hypogonadism.
Background References:
- Li, N., et al. J. Clin. Endocrinol. Metab. 95 (9), E104-E111 (2010) :
- Nedumaran, B., et al. J. Biol. Chem. 285(12):9221-9232(2010)
- Kinsey, M., et al. Cancer Res. 69(23):9047-9055(2009)
- Nagl, F., et al. Am. J. Physiol., Cell Physiol. 297 (5), C1146-C1156 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NR0B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human NR0B1.
NCBI Gene ID #:
190
NCBI Official Name:
Nuclear receptor subfamily 0 group B member 1
NCBI Official Symbol:
NR0B1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
P51843
Protein GI Number:
20532385
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
P51843
User NOte:
Optimal dilutions for each application to be determined by the researcher.