LGALS3 Antibody
| Code | Size | Price |
|---|
| PSI-57-225-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3, MAC2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the galectin family of
carbohydrate binding proteins. Members of this protein family have
an affinity for beta-galactosides. The encoded protein is
characterized by an N-terminal proline-rich tandem repeat domain
and a single C-terminal carbohydrate recognition domain. This
protein can self-associate through the N-terminal domain allowing
it to bind to multivalent saccharide ligands. This protein
localizes to the extracellular matrix, the cytoplasm and the
nucleus. This protein plays a role in numerous cellular functions
including apoptosis, innate immunity, cell adhesion and T-cell
regulation. Alternate splicing results in multiple transcript
variants.
Background References:
- Salomonsson, E., et al. J. Biol. Chem. 285(45):35079-35091(2010)
- Debierre-Grockiego, F., et al. J. Biol. Chem. 285(43):32744-32750(2010)
- Zhou, J.Y., et al. J. Proteome Res. 9(10):5133-5141(2010)
- Markowska, A.I., et al. J. Exp. Med. 207(9):1981-1993(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LGALS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-196 amino acids from the C-terminal region of human LGALS3.
NCBI Gene ID #:
3958
NCBI Official Name:
Galectin-3
NCBI Official Symbol:
LGALS3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
P17931
Protein GI Number:
215274262
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
P17931
User NOte:
Optimal dilutions for each application to be determined by the researcher.