SPG7 Antibody
| Code | Size | Price |
|---|
| PSI-56-453-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Paraplegin, 3424-, Spastic paraplegia 7 protein, SPG7, CAR, CMAR, PGN
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a nuclear-encoded mitochondrial
metalloprotease protein that is a member of the AAA (ATPases
associated with a variety of cellular activities) protein family.
Members of this protein family share an ATPase domain and have
roles in diverse cellular processes including membrane trafficking,
intracellular motility, organelle biogenesis, protein folding, and
proteolysis. Two transcript variants encoding distinct isoforms
have been identified for this gene. Mutations associated with this
gene cause autosomal recessive spastic paraplegia 7. [provided by
RefSeq].
Background References:
- Warnecke, T., et al. Mov. Disord. 25(4):413-420(2010)
- Augustin, S., et al. Mol. Cell 35(5):574-585(2009)
- Karlberg, T., et al. PLoS ONE(10), E6975 (2009) :
- Brugman, F., et al. Neurology 71(19):1500-1505(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SPG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-141 amino acids from the Central region of human SPG7.
NCBI Gene ID #:
6687
NCBI Official Name:
Paraplegin
NCBI Official Symbol:
SPG7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
Q9UQ90
Protein GI Number:
116242796
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
Q9UQ90
User NOte:
Optimal dilutions for each application to be determined by the researcher.