OTX2 Antibody
| Code | Size | Price |
|---|
| PSI-55-983-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Homeobox protein OTX2, Orthodenticle homolog 2, OTX2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
This gene encodes a member of the bicoid sub-family of
homeodomain-containing transcription factors. The encoded protein
acts as a transcription factor and may play a role in brain and
sensory organ development. A similar protein in mice is required
for proper forebrain development. Two transcript variants encoding
distinct isoforms have been identified for this gene. Other
alternative splice variants may exist, but their full length
sequences have not been determined.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Masuda, T., et al. J. Biol. Chem. 285(35):26933-26944(2010)
- Gonzalez-Rodriguez, J., et al. BrOphthalmol 94(8):1100-1104(2010)
- Chung, C.Y., et al. Brain 133 (PT 7), 2022-2031 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Xenopus
Immunogen:
This OTX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human OTX2.
NCBI Gene ID #:
5015
NCBI Official Name:
Homeobox protein OTX2
NCBI Official Symbol:
OTX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
P32243
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
P32243
User NOte:
Optimal dilutions for each application to be determined by the researcher.