NTF3 Antibody

ProSci
Product Code: PSI-63-188
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-188-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Formalin-fixed and paraffin-embedded human brain tissue reacted with NTF3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
2 / 2
Western blot analysis in HL-60 cell line lysates (35ug/lane).

Formalin-fixed and paraffin-embedded human brain tissue reacted with NTF3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Western blot analysis in HL-60 cell line lysates (35ug/lane).

Further Information

Additional Names:
Neurotrophin-3, NT-3, HDNF, Nerve growth factor 2, NGF-2, Neurotrophic factor, NTF3
Application Note:
For IHC-P starting dilution is: 1:10~50

For WB starting dilution is: 1:1000
Background:
NTF3 is a member of the neurotrophin family that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
Background References:
  • Hossain,W.A., J. Neurosci. Res. 86 (11), 2376-2391 (2008)
  • Mercader,J.M., Hum. Mol. Genet. 17 (9), 1234-1244 (2008)
  • Kalcheim,C.,Proc. Natl. Acad. Sci. U.S.A. 89 (5), 1661-1665 (1992)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Pig, Rat
Immunogen:
This NTF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the Central region of human NTF3.
NCBI Gene ID #:
4908
NCBI Official Name:
Neurotrophin-3
NCBI Official Symbol:
NTF3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
P20783
Protein GI Number:
128581
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
P20783
User NOte:
Optimal dilutions for each application to be determined by the researcher.