PAX6 Antibody
| Code | Size | Price |
|---|
| PSI-56-734-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
This gene encodes paired box gene 6, one of many human
homologs of the Drosophila melanogaster gene prd. In addition to
the hallmark feature of this gene family, a conserved paired box
domain, the encoded protein also contains a homeo box domain. Both
domains are known to bind DNA, and function as regulators of gene
transcription. This gene is expressed in the developing nervous
system, and in developing eyes. Mutations in this gene are known to
cause ocular disorders such as aniridia and Peter's anomaly.
Alternatively spliced transcript variants encoding either the same
or different isoform have been found for this gene. [provided by
RefSeq].
Background References:
- Gosmain, Y., et al. J. Biol. Chem. 285(43):33381-33393(2010)
- Vuzman, D., et al. Biophys. J. 99(4):1202-1211(2010)
- Zhang, X., et al. Cell Stem Cell 7(1):90-100(2010)
- Bremond-Gignac, D., et al. Mol. Vis. 16, 1705-1711 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PAX6 antibody is generated from rabbits immunized with a recombinant protein from human PAX6.
NCBI Gene ID #:
5080
NCBI Official Name:
Paired box protein Pax-6
NCBI Official Symbol:
PAX6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
P26367
Protein GI Number:
6174889
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
P26367
User NOte:
Optimal dilutions for each application to be determined by the researcher.