AUP1 Antibody
| Code | Size | Price |
|---|
| PSI-58-566-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ancient ubiquitous protein 1, AUP1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that contains a domain with
homology to the ancient conserved region of the archain 1 gene and
a domain that may be involved in binding ubiquitin-conjugating
enzymes. The protein encoded by this gene has been shown to bind to
the conserved membrane-proximal sequence of the cytoplasmic tail of
integrin alpha(IIb) subunits. These subunits play a crucial role in
the integrin alpha(IIb)beta(3) inside-out signalling in platelets
and megakaryocytes that leads to platelet aggregation and thrombus
formation. This gene overlaps the gene for mitochondrial serine
protease 25.
Background References:
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
- Kato, A., et al. J. Biol. Chem. 277(32):28934-28941(2002)
- Karpisheva, K.V., et al. Tsitologiia 44(9):846-851(2002)
- Karpisheva, K.V., et al. Tsitologiia 44(9):839-845(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This AUP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the C-terminal region of human AUP1.
NCBI Gene ID #:
550
NCBI Official Name:
Ancient ubiquitous protein 1
NCBI Official Symbol:
AUP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
Q9Y679
Protein GI Number:
12643958
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity
Swissprot #:
Q9Y679
User NOte:
Optimal dilutions for each application to be determined by the researcher.