TXNRD3 Antibody
| Code | Size | Price |
|---|
| PSI-60-626-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Thioredoxin reductase 3, Thioredoxin and glutathione reductase, Thioredoxin reductase TR2, TXNRD3 {ECO:0000312|EMBL:AAH500321}
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the family of pyridine
nucleotide oxidoreductases. This protein catalyzes the reduction of
thioredoxin, and is implicated in the defense against oxidative
stress. It contains a selenocysteine (Sec) residue (which is
essential for catalytic activity), encoded by a UGA codon, at the
penultimate C-terminal position. The 3' UTR of Sec-containing genes
have a common stem-loop structure, the sec insertion sequence
(SECIS), which is necessary for the recognition of UGA as a Sec
codon rather than as a stop signal. Alternatively spliced
transcript variants encoding different isoforms have been found for
this gene.
Background References:
- Gerashchenko, M.V., et al. J. Biol. Chem. 285(7):4595-4602(2010)
- Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)
- Harris, S.E., et al. BMC Genet. 8, 43 (2007) :
- Kryukov, G.V., et al. Science 300(5624):1439-1443(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TXNRD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human TXNRD3.
NCBI Gene ID #:
114112
NCBI Official Name:
Thioredoxin reductase 3
NCBI Official Symbol:
TXNRD3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
71 kDa
Protein Accession #:
Q86VQ6
Protein GI Number:
510120859
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity
Swissprot #:
Q86VQ6
User NOte:
Optimal dilutions for each application to be determined by the researcher.