GLUD2 Antibody

ProSci
Product Code: PSI-60-872
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-872-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Glutamate dehydrogenase 2, mitochondrial, GDH 2, GLUD2, GLUDP1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.
Background References:
  • Spanaki, C., et al. J. Biol. Chem. 285(22):16748-16756(2010)
  • Plaitakis, A., et al. Eur. J. Hum. Genet. 18(3):336-341(2010)
  • Zaganas, I., et al. Neurochem. Int. 55 (1-3), 52-63 (2009) :
  • Mastorodemos, V., et al. Biochem. Cell Biol. 87(3):505-516(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GLUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human GLUD2.
NCBI Gene ID #:
2747
NCBI Official Name:
Glutamate dehydrogenase 2, mitochondrial
NCBI Official Symbol:
GLUD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
P49448
Protein GI Number:
13432152
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Neuroscience,Signal Transduction
Swissprot #:
P49448
User NOte:
Optimal dilutions for each application to be determined by the researcher.