AFG3L2 Antibody

ProSci
Product Code: PSI-56-926
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-926-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453,MCF-7,Jurkat cell line lysates (35ug/lane).
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AFG3L2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in MDA-MB453,MCF-7,Jurkat cell line lysates (35ug/lane).
AFG3L2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
AFG3-like protein 2, 3424-, Paraplegin-like protein, AFG3L2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
Background References:
  • Edener, U., et al. Eur. J. Hum. Genet. 18(8):965-968(2010)
  • Di Bella, D., et al. Nat. Genet. 42(4):313-321(2010)
  • Augustin, S., et al. Mol. Cell 35(5):574-585(2009)
  • Mariotti, C., et al. Cerebellum 7(2):184-188(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This AFG3L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the N-terminal region of human AFG3L2.
NCBI Gene ID #:
10939
NCBI Official Name:
AFG3-like protein 2
NCBI Official Symbol:
AFG3L2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
89 kDa
Protein Accession #:
Q9Y4W6
Protein GI Number:
126302516
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q9Y4W6
User NOte:
Optimal dilutions for each application to be determined by the researcher.