STC1 Antibody
| Code | Size | Price |
|---|
| PSI-58-050-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Stanniocalcin-1, STC-1, STC1, STC
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a secreted, homodimeric glycoprotein
that is expressed in a wide variety of tissues and may have
autocrine or paracrine functions. The gene contains a 5' UTR rich
in CAG trinucleotide repeats. The encoded protein contains 11
conserved cysteine residues and is phosphorylated by protein kinase
C exclusively on its serine residues. The protein may play a role
in the regulation of renal and intestinal calcium and phosphate
transport, cell metabolism, or cellular calcium/phosphate
homeostasis. Overexpression of human stanniocalcin 1 in mice
produces high serum phosphate levels, dwarfism, and increased
metabolic rate. This gene has altered expression in hepatocellular,
ovarian, and breast cancers.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Liu, G., et al. J. Natl. Cancer Inst. 102(11):812-827(2010)
- Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This STC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-221 amino acids from the C-terminal region of human STC1.
NCBI Gene ID #:
6781
NCBI Official Name:
Stanniocalcin-1
NCBI Official Symbol:
STC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
P52823
Protein GI Number:
1706175
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P52823
User NOte:
Optimal dilutions for each application to be determined by the researcher.