PRSS1 Antibody

ProSci
Product Code: PSI-55-377
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-377-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Further Information

Additional Names:
Trypsin-1, Beta-trypsin, Cationic trypsinogen, Serine protease 1, Trypsin I, Alpha-trypsin chain 1, Alpha-trypsin chain 2, PRSS1, TRP1, TRY1, TRYP1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.
Background References:
  • Joergensen, M.T., et al. Am. J. Gastroenterol. 105(8):1876-1883(2010)
  • Gasiorowska, A., et al. Dig. Dis. Sci. (2010) In press :
  • Szmola, R., et al. J. Med. Genet. 47(5):348-350(2010)
  • Nakanuma, S., et al. Int. J. Oncol. 36(4):793-800(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PRSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 amino acids from the Central region of human PRSS1.
NCBI Gene ID #:
5644
NCBI Official Name:
Trypsin-1
NCBI Official Symbol:
PRSS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
P07477
Protein GI Number:
136408
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P07477
User NOte:
Optimal dilutions for each application to be determined by the researcher.