NHEDC2 Antibody
Code | Size | Price |
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PSI-59-420-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Mitochondrial sodium/hydrogen exchanger 9B2, Mitochondrial Na(+)/H(+) exchanger NHA2, Na(+)/H(+) exchanger-like domain-containing protein 2, NHE domain-containing protein 2, Sodium/hydrogen exchanger-like domain-containing protein 2, Solute carrier family 9 subfamily B member 2, SLC9B2, NHA2, NHEDC2
Application Note:
For WB starting dilution is: 1:1000
Background:
Sodium hydrogen antiporters, such as NHEDC2, convert the
proton motive force established by the respiratory chain or the
F1F0 mitochondrial ATPase into sodium gradients that drive other
energy-requiring processes, transduce environmental signals into
cell responses, or function in drug efflux (Xiang et al., 2007
[PubMed 18000046]).
Background References:
- Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
- Schushan, M., et al. J. Mol. Biol. 396(5):1181-1196(2010)
- Fuster, D.G., et al. J. Am. Soc. Nephrol. 19(8):1547-1556(2008)
- Battaglino, R.A., et al. Bone 42(1):180-192(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This NHEDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-486 amino acids from the C-terminal region of human NHEDC2.
NCBI Gene ID #:
133308
NCBI Official Name:
Mitochondrial sodium/hydrogen exchanger 9B2
NCBI Official Symbol:
SLC9B2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
Q86UD5
Protein GI Number:
121944426
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
Q86UD5
User NOte:
Optimal dilutions for each application to be determined by the researcher.