ONECUT1 Antibody

ProSci
Product Code: PSI-56-598
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-598-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in HL-60 cell line lysates (35ug/lane).

Western blot analysis in HL-60 cell line lysates (35ug/lane).

Further Information

Additional Names:
Hepatocyte nuclear factor 6, HNF-6, One cut domain family member 1, One cut homeobox 1, ONECUT1, HNF6, HNF6A
Application Note:
For WB starting dilution is: 1:1000
Background:
ONECUT1 is a transcriptional activator. It binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
Background References:
  • Lee, Y.S., et al. Biochem. J. 413(3):559-569(2008)
  • Jiang, X., et al. Oncol. Rep. 19(1):157-163(2008)
  • Lehner, F., et al. FASEB J. 21(7):1445-1462(2007)
  • Rausa, F.M. III, et al. J. Biol. Chem. 279(41):43070-43076(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This ONECUT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-385 amino acids from the C-terminal region of human ONECUT1.
NCBI Gene ID #:
3175
NCBI Official Name:
Hepatocyte nuclear factor 6
NCBI Official Symbol:
ONECUT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
Q9UBC0
Protein GI Number:
13627184
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
Q9UBC0
User NOte:
Optimal dilutions for each application to be determined by the researcher.