SECISBP2 Antibody
| Code | Size | Price |
|---|
| PSI-58-088-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Selenocysteine insertion sequence-binding protein 2, SECIS-binding protein 2, SECISBP2, SBP2
Application Note:
For WB starting dilution is: 1:1000
Background:
The incorporation of selenocysteine into a protein
requires the concerted action of an mRNA element called a sec
insertion sequence (SECIS), a selenocysteine-specific translation
elongation factor and a SECIS binding protein. With these elements
in place, a UGA codon can be decoded as selenocysteine. The gene
described in this record encodes a nuclear protein that functions
as a SECIS binding protein. Mutations in this gene have been
associated with a reduction in activity of a specific thyroxine
deiodinase, a selenocysteine-containing enzyme, and abnormal
thyroid hormone metabolism.
Background References:
- Meplan, C., et al. Carcinogenesis 31(6):1074-1079(2010)
- Papp, L.V., et al. Antioxid. Redox Signal. 12(7):797-808(2010)
- Di Cosmo, C., et al. J. Clin. Endocrinol. Metab. 94(10):4003-4009(2009)
- Olieric, V., et al. Biochimie 91(8):1003-1009(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This SECISBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 501-530 amino acids from the Central region of human SECISBP2.
NCBI Gene ID #:
79048
NCBI Official Name:
Selenocysteine insertion sequence-binding protein 2
NCBI Official Symbol:
SECISBP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
95 kDa
Protein Accession #:
Q96T21
Protein GI Number:
52788293
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
Q96T21
User NOte:
Optimal dilutions for each application to be determined by the researcher.