NOXA1 Antibody

ProSci
Product Code: PSI-64-008
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-64-008-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of NOXA1 Antibody in MDA-MB435 cell line lysates (35ug/lane)

Western blot analysis of NOXA1 Antibody in MDA-MB435 cell line lysates (35ug/lane)

Further Information

Additional Names:
NADPH oxidase activator 1, NOX activator 1, Antigen NY-CO-31, NCF2-like protein, P67phox-like factor, p51-nox, NOXA1, P51NOX
Application Note:
For WB starting dilution is: 1:1000
Background:
NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). The NOX activator NOXA1 can stimulate both NOX1 (MIM 300225) and NOX2 (CYBB; MIM 300481), but it appears to be more effective in activating NOX1 (Opitz et al., 2007 [PubMed 17189823]).[supplied by OMIM].
Background References:
  • Niu, X.L., et al. Circulation 121(4):549-559(2010)
  • Pacquelet, S., et al. J. Biol. Chem. 283(36):24649-24658(2008)
  • Honjo, T., et al. Endothelium 15(3):137-141(2008)
  • Kim, J.S., et al. J. Biol. Chem. 282(48):34787-34800(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NOXA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-478 amino acids from the C-terminal region of human NOXA1.
NCBI Gene ID #:
10811
NCBI Official Name:
NADPH oxidase activator 1
NCBI Official Symbol:
NOXA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
Q86UR1
Protein GI Number:
74759404
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
Q86UR1
User NOte:
Optimal dilutions for each application to be determined by the researcher.