FDXR Antibody

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ProSci
Product Code: PSI-58-283
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-283-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Y79 cell line lysates (35ug/lane).
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Western blot analysis in Y79 cell line lysates (35ug/lane).

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Further Information

Additional Names:
NADPH:adrenodoxin oxidoreductase, mitochondrial, AR, Adrenodoxin reductase, Ferredoxin--NADP(+) reductase, Ferredoxin reductase, FDXR, ADXR
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants of this gene have been described although the full-length nature of only two that encode different isoforms have been determined.
Background References:
  • Trapasso, F., et al. J. Biol. Chem. 283(20):13736-13744(2008)
  • Araya, Z., et al. Biochim. Biophys. Acta 1632 (1-3), 40-47 (2003) :
  • Thiboutot, D., et al. J. Invest. Dermatol. 120(6):905-914(2003)
  • Liu, G., et al. Oncogene 21(47):7195-7204(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FDXR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 459-487 amino acids from the C-terminal region of human FDXR.
NCBI Gene ID #:
2232
NCBI Official Name:
NADPH:adrenodoxin oxidoreductase, mitochondrial
NCBI Official Symbol:
FDXR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
P22570
Protein GI Number:
85681283
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P22570
User NOte:
Optimal dilutions for each application to be determined by the researcher.