SRGN Antibody
| Code | Size | Price |
|---|
| PSI-56-327-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Serglycin, Hematopoietic proteoglycan core protein, Platelet proteoglycan core protein, PPG, Secretory granule proteoglycan core protein, SRGN, PRG, PRG1
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a protein best known as a hematopoietic
cell granule proteoglycan. Proteoglycans stored in the secretory
granules of many hematopoietic cells also contain a
protease-resistant peptide core, which may be important for
neutralizing hydrolytic enzymes. This encoded protein was found to
be associated with the macromolecular complex of granzymes and
perforin, which may serve as a mediator of granule-mediated
apoptosis. Two transcript variants, only one of them
protein-coding, have been found for this gene. [provided by
RefSeq].
Background References:
- Ma, D., et al. Pediatr Blood Cancer 50(5):1067-1069(2008)
- Kolset, S.O., et al. Glycoconj. J. 25(4):305-311(2008)
- Theocharis, A.D., et al. J. Biol. Chem. 281(46):35116-35128(2006)
- Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SRGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the C-terminal region of human SRGN.
NCBI Gene ID #:
5552
NCBI Official Name:
Serglycin
NCBI Official Symbol:
SRGN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
18 kDa
Protein Accession #:
P10124
Protein GI Number:
269849659
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P10124
User NOte:
Optimal dilutions for each application to be determined by the researcher.