OLR1 Antibody

ProSci
Product Code: PSI-63-669
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-669-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from HUVEC cell line, using OLR1 Antibody at 1:1000.
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Western blot analysis of lysates from Hela cell line , human liver and placenta tissue lysate(from left to right), using OLR1 Antibody at 1:1000 at each lane.
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Western blot analysis of lysates from A549, HUVEC cell line and human liver, placenta tissue lysate(from left to right), using OLR1 Antibody at 1:1000 at each lane.
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Western blot analysis of OLR1 Antibody in HL-60 cell line lysates (35ug/lane)
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Western blot analysis of OLR1 using rabbit polyclonal OLR1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OLR1 gene (Lane 2).
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Formalin-fixed and paraffin-embedded human brain tissue reacted with OLR1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Western blot analysis of lysate from HUVEC cell line, using OLR1 Antibody at 1:1000.
Western blot analysis of lysates from Hela cell line , human liver and placenta tissue lysate(from left to right), using OLR1 Antibody at 1:1000 at each lane.
Western blot analysis of lysates from A549, HUVEC cell line and human liver, placenta tissue lysate(from left to right), using OLR1 Antibody at 1:1000 at each lane.
Western blot analysis of OLR1 Antibody in HL-60 cell line lysates (35ug/lane)
Western blot analysis of OLR1 using rabbit polyclonal OLR1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OLR1 gene (Lane 2).
Formalin-fixed and paraffin-embedded human brain tissue reacted with OLR1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Further Information

Additional Names:
Oxidized low-density lipoprotein receptor 1, Ox-LDL receptor 1, C-type lectin domain family 8 member A, Lectin-like oxidized LDL receptor 1, LOX-1, Lectin-like oxLDL receptor 1, hLOX-1, Lectin-type oxidized LDL receptor 1, Oxidized low-density lipoprotein receptor 1, soluble form, OLR1, CLEC8A, LOX1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
OLR1 is a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor.
Background References:
  • Predazzi,I.M.,et.al., Ann. Hum. Biol. 37 (2), 136-148 (2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This OLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human OLR1.
NCBI Gene ID #:
4973
NCBI Official Name:
Oxidized low-density lipoprotein receptor 1
NCBI Official Symbol:
OLR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
P78380
Protein GI Number:
73621335
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P78380
User NOte:
Optimal dilutions for each application to be determined by the researcher.