IMP2L Antibody

ProSci
Product Code: PSI-64-225
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-64-225-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of IMP2L Antibody in Jurkat cell line lysates (35ug/lane)
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IMP2L Antibody IHC analysis in formalin fixed and paraffin embedded rat lung tisssue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis of IMP2L Antibody in Jurkat cell line lysates (35ug/lane)
IMP2L Antibody IHC analysis in formalin fixed and paraffin embedded rat lung tisssue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Mitochondrial inner membrane protease subunit 2, 3421-, IMP2-like protein, IMMP2L
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
IMP2L complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 (IMMP1L; MIM 612323) and IMP2 are the catalytic subunits of the IMP complex.
Background References:
  • Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
  • Trynka, G., et al. Gut 58(8):1078-1083(2009)
  • de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This IMP2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-109 amino acids from the Central region of human IMP2L.
NCBI Gene ID #:
83943
NCBI Official Name:
Mitochondrial inner membrane protease subunit 2
NCBI Official Symbol:
IMMP2L
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
Q96T52
Protein GI Number:
74752143
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
Q96T52
User NOte:
Optimal dilutions for each application to be determined by the researcher.