RT4I1 Antibody

ProSci
Product Code: PSI-55-409
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-409-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 3
Western blot analysis in WiDr cell line lysates (35ug/lane).
2 / 3
RT4I1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
3 / 3

Western blot analysis in WiDr cell line lysates (35ug/lane).
RT4I1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Reticulon-4-interacting protein 1, mitochondrial, NOGO-interacting mitochondrial protein, RTN4IP1, NIMP
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
This gene encodes a novel mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. The interaction of reticulon 4 with mitochondrial proteins may provide insight into the mechanisms for reticulon-induced inhibition of neurite growth.
Background References:
  • Rose, J. Phd, et al. Mol. Med. (2010) In press :
  • Mungall, A.J., et al. Nature 425(6960):805-811(2003)
  • Domeniconi, M., et al. Neuron 35(2):283-290(2002)
  • Hu, W.H., et al. J. Neurochem. 81(1):36-45(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RT4I1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-363 amino acids from the C-terminal region of human RT4I1.
NCBI Gene ID #:
84816
NCBI Official Name:
Reticulon-4-interacting protein 1, mitochondrial
NCBI Official Symbol:
RTN4IP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q8WWV3
Protein GI Number:
76789669
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
Q8WWV3
User NOte:
Optimal dilutions for each application to be determined by the researcher.