GSR Antibody
| Code | Size | Price |
|---|
| PSI-56-200-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Glutathione reductase, mitochondrial, GR, GRase, GSR, GLUR, GRD1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a member of the class-I pyridine
nucleotide-disulfide oxidoreductase family. This enzyme is a
homodimeric flavoprotein. It is a central enzyme of cellular
antioxidant defense, and reduces oxidized glutathione disulfide
(GSSG) to the sulfhydryl form GSH, which is an important cellular
antioxidant. Rare mutations in this gene result in hereditary
glutathione reductase deficiency. Multiple alternatively spliced
transcript variants encoding different isoforms have been found.
Background References:
- Satoh, N., et al. Biochem. Genet. 48 (9-10), 816-821 (2010) :
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GSR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-408 amino acids from the C-terminal region of human GSR.
NCBI Gene ID #:
2936
NCBI Official Name:
Glutathione reductase, mitochondrial
NCBI Official Symbol:
GSR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
P00390
Protein GI Number:
14916998
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P00390
User NOte:
Optimal dilutions for each application to be determined by the researcher.