PPM1G Antibody
Code | Size | Price |
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PSI-57-704-400ul | 400ul | £626.00 |
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Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Protein phosphatase 1G, Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, PP2C-gamma, Protein phosphatase magnesium-dependent 1 gamma, PPM1G, PPM1C
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the PP2C
family of Ser/Thr protein phosphatases. PP2C family members are
known to be negative regulators of cell stress response pathways.
This phosphatase is found to be responsible for the
dephosphorylation of Pre-mRNA splicing factors, which is important
for the formation of functional spliceosome. Studies of a similar
gene in mice suggested a role of this phosphatase in regulating
cell cycle progression.
Background References:
- Dick, D.M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (6), 1179-1188 (2010) :
- Suh, E.J., et al. Biochem. Biophys. Res. Commun. 386(3):467-470(2009)
- Petri, S., et al. J. Cell Biol. 179(3):451-465(2007)
- Allemand, E., et al. Nat. Struct. Mol. Biol. 14(7):630-638(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse
Immunogen:
This PPM1G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the N-terminal region of human PPM1G.
NCBI Gene ID #:
5496
NCBI Official Name:
Protein phosphatase 1G
NCBI Official Symbol:
PPM1G
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
O15355
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
O15355
User NOte:
Optimal dilutions for each application to be determined by the researcher.