Mouse Sgk1 Antibody
| Code | Size | Price |
|---|
| PSI-60-192-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1, Sgk1, Sgk
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a serine/threonine protein kinase that
plays an important role in cellular stress response. This kinase
activates certain potassium, sodium, and chloride channels,
suggesting an involvement in the regulation of processes such as
cell survival, neuronal excitability, and renal sodium excretion.
This enzyme is activated by protein phosphorylation and degraded
via the ubiquitination and proteasome pathway. Multiple transcript
variants encoding different isoforms have been found for this gene.
A pseudogene of this gene was identified on chromosome 12.
Background References:
- Gao, D., et al. Mol. Cell 39(5):797-808(2010)
- Catela, C., et al. Dev. Dyn. 239(8):2149-2160(2010)
- Hallows, K.R., et al. J. Biol. Chem. 285(28):21671-21678(2010)
- Kaji, T., et al. Front Biosci (Elite Ed) 2, 1355-1361 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Immunogen:
This Mouse Sgk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-352 amino acids from the C-terminal region of mouse Sgk1.
NCBI Gene ID #:
20393
NCBI Official Name:
Serine/threonine-protein kinase Sgk1
NCBI Official Symbol:
Sgk1
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
Q9WVC6
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q9WVC6
User NOte:
Optimal dilutions for each application to be determined by the researcher.