PPP2R1A Antibody
| Code | Size | Price |
|---|
| PSI-60-680-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Medium tumor antigen-associated 61 kDa protein, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha, PPP2R1A
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a constant regulatory subunit of protein
phosphatase 2. Protein phosphatase 2 is one of the four major
Ser/Thr phosphatases, and it is implicated in the negative control
of cell growth and division. It consists of a common heteromeric
core enzyme, which is composed of a catalytic subunit and a
constant regulatory subunit, that associates with a variety of
regulatory subunits. The constant regulatory subunit A serves as a
scaffolding molecule to coordinate the assembly of the catalytic
subunit and a variable regulatory B subunit. This gene encodes an
alpha isoform of the constant regulatory subunit A. Alternatively
spliced transcript variants have been described. [provided by
RefSeq].
Background References:
- Jones, S., et al. Science 330(6001):228-231(2010)
- Schmitz, M.H., et al. Nat. Cell Biol. 12(9):886-893(2010)
- Heikkinen, P.T., et al. J. Biol. Chem. 285(6):3740-3749(2010)
- Dupont, W.D., et al. Cancer 116(1):8-19(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig
Immunogen:
This PPP2R1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-481 amino acids from the C-terminal region of human PPP2R1A.
NCBI Gene ID #:
5518
NCBI Official Name:
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
NCBI Official Symbol:
PPP2R1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
P30153
Protein GI Number:
143811355
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
P30153
User NOte:
Optimal dilutions for each application to be determined by the researcher.