ITA6 Antibody

ProSci
Product Code: PSI-63-956
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-956-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A431 cell line and human placenta tissue lysates (35ug/lane).

Western blot analysis in A431 cell line and human placenta tissue lysates (35ug/lane).

Further Information

Additional Names:
Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD49f, Integrin alpha-6 heavy chain, Integrin alpha-6 light chain, Processed integrin alpha-6, Alpha6p, ITGA6
Application Note:
For WB starting dilution is: 1:1000
Background:
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Background References:
  • Kim, T.H., et al. Mol. Cancer Res. 7(10):1605-1612(2009)
  • Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
  • Boroujerdnia, M.G., et al. Pak. J. Biol. Sci. 12(4):360-366(2009)
  • Dai, J.Y., et al. BMC Cancer 9, 337 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ITA6 antibody is generated from rabbits immunized with ITA6 recombinant protein.
NCBI Gene ID #:
3655
NCBI Official Name:
Integrin alpha-6
NCBI Official Symbol:
ITGA6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
127 kDa
Protein Accession #:
P23229
Protein GI Number:
519668687
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
P23229
User NOte:
Optimal dilutions for each application to be determined by the researcher.