HIPK2 Antibody
Code | Size | Price |
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PSI-62-972-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Homeodomain-interacting protein kinase 2, hHIPk2, HIPK2
Application Note:
For WB starting dilution is: 1:1000
Background:
HIPK2, a member of the KIPK subfamily of Ser/Thr protein kinases, phosphorylates homeodomain transcription factors. It may play a role as a corepressor for homeodomain transcription factors. This nuclear protein has been shown to interact with TRADD. It is highly expressed in neuronal tissues, heart and kidney, and weakly expressed in a ubiquitous way. HIPK2 is a target for sumoylation, and when conjugated it is directed to nuclear speckles
Background References:
- Li, X., et al., Biochem. Biophys. Res. Commun. 277(2):513-517 (2000).
- Wang, Y., et al., Biochim. Biophys. Acta 1518 (1-2), 168-172 (2001).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This HIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-372 amino acids from human HIPK2.
NCBI Gene ID #:
28996
NCBI Official Name:
Homeodomain-interacting protein kinase 2
NCBI Official Symbol:
HIPK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
131 kDa
Protein Accession #:
Q9H2X6
Protein GI Number:
21431782
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q9H2X6
User NOte:
Optimal dilutions for each application to be determined by the researcher.