FNTA Antibody
| Code | Size | Price |
|---|
| PSI-59-614-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha, FNTA
Application Note:
For WB starting dilution is: 1:1000
Background:
Prenyltransferases can attach either a farnesyl group or a
geranylgeranyl group in thioether linkage to the cysteine residue
of proteins with a C-terminal CAAX box. CAAX
geranylgeranyltransferase and CAAX farnesyltransferase are
heterodimers that share the same alpha subunit but have different
beta subunits. This gene encodes the alpha subunit of these
transferases. Alternative splicing results in multiple transcript
variants. Related pseudogenes have been identified on chromosomes
11 and 13.
Background References:
- Lipkin, S.M., et al. Cancer Prev Res (Phila Pa) 3(5):597-603(2010)
- Fontaine-Bisson, B., et al. J. Mol. Med. 88(2):193-201(2010)
- Zhou, J., et al. J. Biol. Chem. 284(15):9648-9655(2009)
- Veluthakal, R., et al. Diabetes 56(1):204-210(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human FNTA.
NCBI Gene ID #:
2339
NCBI Official Name:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
NCBI Official Symbol:
FNTA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
P49354
Protein GI Number:
1346694
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
P49354
User NOte:
Optimal dilutions for each application to be determined by the researcher.