ARHGEF4 Antibody
| Code | Size | Price |
|---|
| PSI-60-045-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor 1, Asef, Asef1, ARHGEF4, KIAA1112
Application Note:
For WB starting dilution is: 1:1000
Background:
Rho GTPases play a fundamental role in numerous cellular
processes that are initiated by extracellular stimuli that work
through G protein coupled receptors. The encoded protein may form
complex with G proteins and stimulate Rho-dependent signals. This
protein is similar to rat collybistin protein. Alternative splicing
of this gene generates two transcript variants which encode
different isoforms. Also there is possibility for the usage of
multiple polyadenylation sites for this gene.
Background References:
- Lyons, R., et al. Leuk. Res. 34(1):109-115(2010)
- Kawasaki, Y., et al. J. Biol. Chem. 284(33):22436-22443(2009)
- Itoh, R.E., et al. J. Cell. Sci. 121 (PT 16), 2635-2642 (2008) :
- Kurzik-Dumke, U., et al. Cell. Signal. 19(9):1973-1985(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ARHGEF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-599 amino acids from the C-terminal region of human ARHGEF4.
NCBI Gene ID #:
101930241, 50649
NCBI Official Name:
Rho guanine nucleotide exchange factor 4
NCBI Official Symbol:
ARHGEF4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q9NR80
Protein GI Number:
229463003
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q9NR80
User NOte:
Optimal dilutions for each application to be determined by the researcher.