KIRREL Antibody
| Code | Size | Price |
|---|
| PSI-60-752-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Kin of IRRE-like protein 1, Kin of irregular chiasm-like protein 1, Nephrin-like protein 1, KIRREL, KIRREL1, NEPH1
Application Note:
For WB starting dilution is: 1:1000
Background:
NEPH1 is a member of the nephrin-like protein family,
which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The
cytoplasmic domains of these proteins interact with the C terminus
of podocin (NPHS2; MIM 604766), and the genes are expressed in
kidney podocytes, cells involved in ensuring size- and
charge-selective ultrafiltration (Sellin et al., 2003 [PubMed
12424224]).
Background References:
- Machuca, E., et al. J. Am. Soc. Nephrol. 21(7):1209-1217(2010)
- Wagner, M.C., et al. J. Biol. Chem. 283(51):35579-35589(2008)
- Hartleben, B., et al. J. Biol. Chem. 283(34):23033-23038(2008)
- Harita, Y., et al. J. Biol. Chem. 283(14):9177-9186(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This KIRREL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-534 amino acids from the C-terminal region of human KIRREL.
NCBI Gene ID #:
55243
NCBI Official Name:
Kin of IRRE-like protein 1
NCBI Official Symbol:
KIRREL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
Q96J84
Protein GI Number:
54036152
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q96J84
User NOte:
Optimal dilutions for each application to be determined by the researcher.