CLK2 Antibody
| Code | Size | Price |
|---|
| PSI-58-679-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dual specificity protein kinase CLK2, CDC-like kinase 2, CLK2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the CLK family of dual
specificity protein kinases. CLK family members have been shown to
interact with, and phosphorylate, serine- and arginine-rich (SR)
proteins of the spliceosomal complex, which is a part of the
regulatory mechanism that enables the SR proteins to control RNA
splicing. Note that this gene is distinct from TELO2 gene
(GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common
with this gene, but encodes a protein that is involved in telomere
length regulation.
Background References:
- Nam, S.Y., et al. J. Biol. Chem. 285(41):31157-31163(2010)
- Eisenreich, A., et al. Circ. Res. 104(5):589-599(2009)
- Rendtlew Danielsen, J.M., et al. J. Biol. Chem. 284(7):4140-4147(2009)
- Castle, J.C., et al. Nat. Genet. 40(12):1416-1425(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This CLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the Central region of human CLK2.
NCBI Gene ID #:
1196
NCBI Official Name:
Dual specificity protein kinase CLK2
NCBI Official Symbol:
CLK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
P49760
Protein GI Number:
1705919
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
P49760
User NOte:
Optimal dilutions for each application to be determined by the researcher.