DDX3Y Antibody
| Code | Size | Price |
|---|
| PSI-56-646-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
ATP-dependent RNA helicase DDX3Y, DEAD box protein 3, Y-chromosomal, DDX3Y, DBY
Application Note:
For WB starting dilution is: 1:1000
Background:
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this family
are believed to be involved in embryogenesis, spermatogenesis, and
cellular growth and division. This gene encodes a DEAD box protein,
and it has a homolog on the X chromosome. The gene mutation causes
male infertility, Sertoli cell-only syndrome or severe
hypospermatogenesis, suggesting that this gene plays a key role in
the spermatogenic process. Alternatively spliced variants, encoding
the same protein, have been identified.
Background References:
- Rosinski, K.V., et al. Blood 111(9):4817-4826(2008)
- Lardone, M.C., et al. Mol. Hum. Reprod. 13(10):705-712(2007)
- Pope, S.N., et al. J. Steroid Biochem. Mol. Biol. 94 (1-3), 203-208 (2005) :
- Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DDX3Y antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the N-terminal region of human DDX3Y.
NCBI Gene ID #:
8653
NCBI Official Name:
ATP-dependent RNA helicase DDX3Y
NCBI Official Symbol:
DDX3Y
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Protein Accession #:
O15523
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
O15523
User NOte:
Optimal dilutions for each application to be determined by the researcher.