Lamin B2 Antibody

ProSci
Product Code: PSI-62-437
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-437-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of Lamin B2 Antibody in Y79 cell line lysates (35ug/lane)

Western blot analysis of Lamin B2 Antibody in Y79 cell line lysates (35ug/lane)

Further Information

Additional Names:
Lamin-B2, LMNB2, LMN2
Application Note:
For WB starting dilution is: 1:1000
Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B2 is one of the two B type proteins, B2.
Background References:
  • Schumacher,J., FEBS Lett. 580 (26), 6211-6216 (2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Lamin B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human Lamin B2.
NCBI Gene ID #:
84823
NCBI Official Name:
Lamin-B2
NCBI Official Symbol:
LMNB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q03252
Protein GI Number:
23503078
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q03252
User NOte:
Optimal dilutions for each application to be determined by the researcher.