PDCD6IP Antibody
| Code | Size | Price |
|---|
| PSI-60-809-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Programmed cell death 6-interacting protein, PDCD6-interacting protein, ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95, PDCD6IP, AIP1, ALIX, KIAA1375
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein thought to participate in
programmed cell death. Studies using mouse cells have shown that
overexpression of this protein can block apoptosis. In addition,
the product of this gene binds to the product of the PDCD6 gene, a
protein required for apoptosis, in a calcium-dependent manner. This
gene product also binds to endophilins, proteins that regulate
membrane shape during endocytosis. Overexpression of this gene
product and endophilins results in cytoplasmic vacuolization, which
may be partly responsible for the protection against cell death.
Several alternatively spliced transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].
Background References:
- Shi, X., et al. Biochem. J. 431(1):93-102(2010)
- Irie, T., et al. Virology 405(2):334-341(2010)
- Sette, P., et al. J. Virol. 84(16):8181-8192(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PDCD6IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-570 amino acids from the Central region of human PDCD6IP.
NCBI Gene ID #:
10015
NCBI Official Name:
Programmed cell death 6-interacting protein
NCBI Official Symbol:
PDCD6IP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
96 kDa
Protein Accession #:
Q8WUM4
Protein GI Number:
31076831
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q8WUM4
User NOte:
Optimal dilutions for each application to be determined by the researcher.