SFTPA2B Antibody

ProSci
Product Code: PSI-56-290
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-290-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Further Information

Additional Names:
Pulmonary surfactant-associated protein A2, PSP-A, PSPA, SP-A, SP-A2, 35 kDa pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-5, SFTPA2, COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication.
Background References:
  • Silveyra, P., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (4), L523-L534 (2010) :
  • Maitra, M., et al. J. Biol. Chem. 285(29):22103-22113(2010)
  • Wang, G., et al. J. Biol. Chem. 285(16):11998-12010(2010)
  • El Saleeby, C.M., et al. J. Pediatr. 156(3):409-414(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SFTPA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-202 amino acids from the C-terminal region of human SFTPA2B.
NCBI Gene ID #:
729238
NCBI Official Name:
Pulmonary surfactant-associated protein A2
NCBI Official Symbol:
SFTPA2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
Q8IWL1
Protein GI Number:
60416439
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q8IWL1
User NOte:
Optimal dilutions for each application to be determined by the researcher.