STAM2 Antibody
| Code | Size | Price |
|---|
| PSI-57-437-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Signal transducing adapter molecule 2, STAM-2, Hrs-binding protein, STAM2, HBP
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is closely related to
STAM, an adaptor protein involved in the downstream signaling of
cytokine receptors, both of which contain a SH3 domain and the
immunoreceptor tyrosine-based activation motif (ITAM). Similar to
STAM, this protein acts downstream of JAK kinases, and is
phosphorylated in response to cytokine stimulation. This protein
and STAM thus are thought to exhibit compensatory effects on the
signaling pathway downstream of JAK kinases upon cytokine
stimulation.
Background References:
- Stuible, M., et al. J. Biol. Chem. 285(31):23899-23907(2010)
- Rismanchi, N., et al. Traffic 10(2):201-217(2009)
- Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
- Kong, C., et al. J. Biol. Chem. 282(20):15294-15301(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This STAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of human STAM2.
NCBI Gene ID #:
10254
NCBI Official Name:
Signal transducing adapter molecule 2
NCBI Official Symbol:
STAM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
O75886
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
O75886
User NOte:
Optimal dilutions for each application to be determined by the researcher.