CAPN13 Antibody

ProSci
Product Code: PSI-58-495
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-495-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Further Information

Additional Names:
Calpain-13, 3422-, Calcium-activated neutral proteinase 13, CANP 13, CAPN13
Application Note:
For WB starting dilution is: 1:1000
Background:
Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN13 belongs to the calpain large subunit family.
Background References:
  • Taylor, J.Y., et al. Biol Res Nurs 12(2):149-155(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Hillier, L.W., et al. Nature 434(7034):724-731(2005)
  • Dear, T.N., et al. Gene 274 (1-2), 245-252 (2001) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This CAPN13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 537-565 amino acids from the C-terminal region of human CAPN13.
NCBI Gene ID #:
92291
NCBI Official Name:
Calpain-13
NCBI Official Symbol:
CAPN13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
77 kDa
Protein Accession #:
Q6MZZ7
Protein GI Number:
117949375
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q6MZZ7
User NOte:
Optimal dilutions for each application to be determined by the researcher.