PDCD6 Antibody
| Code | Size | Price |
|---|
| PSI-60-784-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Programmed cell death protein 6, Apoptosis-linked gene 2 protein, Probable calcium-binding protein ALG-2, PDCD6, ALG2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a calcium-binding protein belonging to
the penta-EF-hand protein family. Calcium binding is important for
homodimerization and for conformational changes required for
binding to other protein partners. This gene product participates
in T cell receptor-, Fas-, and glucocorticoid-induced programmed
cell death. In mice deficient for this gene product, however,
apoptosis was not blocked suggesting this gene product is
functionally redundant.
Background References:
- Vergarajauregui, S., et al. J. Biol. Chem. 284(52):36357-36366(2009)
- Okumura, M., et al. Biochem. Biophys. Res. Commun. 386(1):237-241(2009)
- Suzuki, H., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 64 (PT 11), 974-977 (2008) :
- Yamada, Y., et al. Cancer Sci. 99(11):2193-2199(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PDCD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human PDCD6.
NCBI Gene ID #:
10016
NCBI Official Name:
Programmed cell death protein 6
NCBI Official Symbol:
PDCD6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
O75340
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
O75340
User NOte:
Optimal dilutions for each application to be determined by the researcher.