SPAG8 Antibody
| Code | Size | Price |
|---|
| PSI-56-675-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sperm-associated antigen 8, HSD-1, Sperm membrane protein 1, SMP-1, Sperm membrane protein BS-84, SPAG8
Application Note:
For WB starting dilution is: 1:1000
Background:
The correlation of anti-sperm antibodies with cases of
unexplained infertility implicates a role for these antibodies in
blocking fertilization. Improved diagnosis and treatment of
immunologic infertility, as well as identification of proteins for
targeted contraception, are dependent on the identification and
characterization of relevant sperm antigens. The protein encoded by
this gene is recognized by sperm agglutinating antibodies from an
infertile woman. This protein is localized in germ cells of the
testis at all stages of spermatogenesis and is localized to the
acrosomal region of mature spermatozoa. Alternatively spliced
variants that encode different protein isoforms have been described
but the full-length sequences of only two have been determined.
Background References:
- Wu, H., et al. FEBS Lett. 584(13):2807-2815(2010)
- Li, R., et al. Cell Biochem. Funct. 27(5):264-268(2009)
- Cheng, G.Y., et al. Asian J. Androl. 9(1):23-29(2007)
- Tang, X., et al. J. Mol. Med. 82(6):383-388(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SPAG8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-411 amino acids from the C-terminal region of human SPAG8.
NCBI Gene ID #:
26206
NCBI Official Name:
Sperm-associated antigen 8
NCBI Official Symbol:
SPAG8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q99932
Protein GI Number:
62511128
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q99932
User NOte:
Optimal dilutions for each application to be determined by the researcher.